I run the Power Service Diesel Clean just about every fill up. There was a great article in a recent Diesel World or Diesel Power magazine that discussed how the boost in cetane works. Seems it works in reverse of octane which slows down ignition to prevent spark knock. Cetane speeds up the combustion. They did say that if there's any boost in power or mileage it's minimal but it did make for a cleaner burn. So I figure if it keeps anything from sooting up I might as well use it. I buy it at WalMart by the gallon because it's cheaper that way, then I just put in 16 -20 ounces when I fill up.