This Website should help you when it comes to the 53 Block. As far as the lift pumps and the Vp's, It's hit or Miss, I was running a factory Vp for 130k miles, added a TST for 20k then added the Fass and Mach 6 Injectors and a silver Bullet turbo for another 20k and still had no problems on a 2000 3500, now my 01 2500 had a VP replaced 2 months before I bought it, threw the TST and FASS on at the same time and has taken a dive with only 30k miles on it.