Joe
If you're towing your trailer I'd schedule three days from Vegas to Hillsboro... JMO
George
Portland to Vegas is a easy 2 day trip. We do the run all the time and always leave early the first day, eat a late lunch in Boise at CrackerBarrell, arrive around 8PM and stay the night in SLC, UT. The next morning sleep in and can still be in Vegas by early afternoon. We will be doing this trip again in 3 weeks. If towing a trailer the HWY 84 route then down 15 would be a piece of cake.
We live in Keizer, OR.