Trying to be as proactive as I can here, I’m wondering if I should prime the inside of the steel I plan to weld up to the frame? Also, when grinding the paint off the existing rail, should I just remove where I’ll be welding?
I would cover as much of the metal you can, but leave clean metal about 1/2" from the weld locations. Then touch up those following welding. Also, the aformentioned POR-15 goes on very thin and penetrate nicely and SEALS seams. The only downside to POR-15, is it's not for UV light, as in sun-light, not a problem for a frame however.. that is don't get it on your skin... it's very, very good at bonding to skin as well, it cures with moisture from the air, and apparantly moisture in you skin! Really it's good stuff, you can even use it on brake calipers, and there is a special POR-15 paint to go over it for UV protection. Did the Calipers on my 2004 Land Rover Disco 2 and they came out great.
On welds, I would concur to be cautious on vertical welds on the frame, because the heat affected zone, adjacent to the weld will be annealed in the process of high heat from the welding.. having said that, I think the frame is regular 36KSI mild steel, and as such there won't be much if any reduction in strength, you'll see the OEM has places with vertical welds. That said, if you can do it without vertical welds, all the better.
The picture above showing the correction of cracks shows how they notch out the entire crack area, and do a drill hole ate the end of the crack, this is to stop spreading of the crack, a standard repair practice for stress cracks, I too had an RV frame that was subject to recall... but I had already repaired it myself before the recall came out. My first quick fix of a simple weld seem over the crack, just cracked again.. but drilling out the crack ends and welding it, as well as fixing the cause of the excessive stress forces has fixed it permanently, I ironically looked at the recall fix, and it was almost identical to what I had already done..
Keep in mind, weld shrinkage is real, and the bigger the welds, the higher the heat, the MORE the shrinkage. a good solid fixture can mitigate some shrinkage as well, but that would be difficult for a frame repair. With the stitch welds proposed any distortion from heat is going to be minimal to non-existant. To get an under standing of what weld shinkage is, think about how hot, and molten the weld bead is, and if a good weld penetrates both base metals.. without restraint holding the parts, when it cools, it contracts, as metals do.. and it changes diminsion, or puts a pre-load stress into the base material. You can actually do welds on only one side of a material to cause, or even correct distortion (do oposing welds to bring it back if distorted by welds on the other side).
Having said all that, the frame is pretty stiff and large compared to the welds you'll need, it's unlikely to be distorted enough for you to notice.
Oh, and a 45 degree cut should be OK, but probably more effort than it's worth. If you weld the top and do a few tacks on the edges, you should have all the strength you'll ever need without the complexity of angle cuts, now if cutting out the rust leaves an angular area already, then by all means, match it for the repair section.
Keep us updated and questions coming. I enjoy these kinds of projects and keeping older vehicles alive, I recently did alot of work on my 2004 Land Rover.. and did POR-15 on all surface frame rust, but lucky for me, WA state rarely uses road salt, so the rust was superficial and no welding needed to correct.. though years back I did fix section of unibody on my 1996 Saturn that had rusted through, it had some prior life in the New England area, and as such road salt.. it got under a plastic panel under the rear passenger door and just ate completly through that steel. I cut out a 12" x 4" section and welded in a new section with my MIG, 100% CO2.
The more I think if it, my welder has had all kinds of uses over the years.. though the most hilarious use was to do an OIL CHANGE. Yep, I used a welder to complete an oil change! Pretty sure few people can say that. The used car I bought had the oil drain plug put on with insane torque, the small hex head rounded, and not even a strong vice grip pliers could grasp it.. so I took a large nut, I think about 7/8" or so.. and welded it to the drain plug.. That provided plenty of grip, and the weld heat no doubt assisted as well.. Ironically the new plug I planned to use was not compatible, so I made the weld look a bit more civilized, and that became the permanent drain plug, that is likely still on that car!