If you are monitoring pressure after all the filters, and just before the CP3 you CAN get a good indication of filter life. Yes the CP3 can draw a vacuum, but that will show up on a pressure gauge. If you still have good pressure then you are not plugged and sucking thru the filters. I usually tell people that if your gauge goes to 2-3 psi WOT then it's time for a new filter, or a bigger pump if your making that much hp. Bosch specs -5 to + 15 psi at the inlet of the CP3, but reading +3 is easier than - 5. This is NOT a substitute for a regular filter change interval, just an additional way to monitor the system.
Todd like to talk trash about internet hype fuel filtration systems, but the simple fact is the one filter on his truck is rated lower than any setup of anyone in this thread. He feels thru his experience that the people that rated his filter were wrong and runs it, that doesn't work for 99% of people. He also talks about internet hype systems, but has yet to mention what system(s), even thou he has been asked repeatedly. He want's to kill the snowball but the way he talks about filters doesn't do much but get his posts ignored. He does have a LOT of good experience and knowledge about the CP3, but doesn't portray it as well as he could when talking filtration. I have asked his filtration recommendation before and he won't give it. We can't discount everything he says, but remember that he does deal mostly with broken CP3's, and that will jade your views.